• A new breed of biotech

• Some questions about biotech that I find interesting

• The pharma industry from Paul Janssen to today: why drugs got harder to develop and what we can do about it

• Latent optima

• Concepts of health and disease as a barrier to progress

• An Enhertu innovation map

• Intelligence as efficient model building

• Pharmaceutical blockbusters: the past, present, and future(?)

• Innovation, sea snails, and the blind professor

• Steelmanning the argument for free drug pricing

• Where are the other Luxturna's? Challenges with gene therapy for inherited retinal diseases

• Reasoning about response rates